The 100th Lord Mayors Centenary Plaque is to be unveiled later this week at the Jean Bishop Integrated Care Centre in Hull.
The blue and gold plaque will honour Hull-born Dr Charlotte Houlton CBE.
Dr Houlton – who died in 1956 at the age of 74 – was chief medical officer of the Women’s Medical Service in India.
She was a pioneer in her field, elected as a Fellow of the Royal College of Obstetricians and Gynaecologists in 1937, before receiving her CBE 2 years later.
The Centenary Plaque project started in 2014, to commemorate the 100 year anniversary of the creation of the role of Lord Mayor in Hull.
It recognises those individuals that had made significant achievements for the benefit of people within and beyond the city.
A trail can be completed of the Centenary Plaques across the city, with free copies of the trail map available from the Welcome Information Centre at Paragon Station, while a trail app, Hull 100, is also available.
Former Councillor and Lord Mayor, Honorary Alderman Mary Glew, initiated the project.
She said: “As the Hull 100 project comes to a close with the unveiling of the 100th plaque, we hope everyone will enjoy following the plaque trail across the city.
“You can discover untold stories of our city’s pioneers, who have transformed our world.
“We could easily have come up with another 100 people!”
Among others who have previously had plaques erected are the Headscarf Revolutionaries, who are honoured at the Maritime Museum.
Ebenezer Cobb Morley, regarded as the founding father of modern football, has a plaque at Hull History Centre.
Mathematician John Venn – the inventor of the Venn diagram – is honoured with a plaque at Drypool Bridge.
A book is to be launched on the 100 people commemorated, authored by city historian Dr Robb Robinson.
He said: “The collection of biographies is about people from all walks of life, whose lives have made some form of national or global impact.
“They are all closely connected with the unique port city of Kingston upon Hull.”
All royalties from the sale of the book will be given to the charities supported by the Lord Mayor, where Councillor Kalvin Neal is this year supporting Dove House Hospice and Hull 4 Heroes.
The Lord Mayor said: “I’m delighted to carry on the Lord Mayors Centenary Plaque project, as we celebrate the inspirational people who were born or lived in Hull.
“These people were pioneers, campaigners, and ground-breakers, and influential not just in the city, but also across the world.”
Leader of Hull City Council, Councillor Mike Ross, said: “It is a great achievement to reach the target of 100 different people being commemorated through the Centenary Plaque scheme.
“We have so much history to mark and celebrate in the city, and this project provides more evidence of how people from Hull have given so much to the world.”